|The MUC18 mcam (Catalog #MBS1491240) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Human Cell surface glycoprotein MUC18 polyclonal Antibody, FITC reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Cell surface glycoprotein MUC18 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the MUC18 mcam for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MUC18 mcam product has the following accession number(s) (GI #71274107) (NCBI Accession #NP_006491.2) (Uniprot Accession #P43121). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit anti-Human Cell surface glycoprotein MUC18 polyclonal Antibody, FITC with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry Immunohistochemistry of paraffin-embedded human placenta at dilution 1:100)
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Storage Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate: FITC. Immunogen: Recombinant Human Cell surface glycoprotein MUC18 Protein
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-18942 / sc-18940 / sc-28667. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MUC18 are readily searchable from our website. Different antibodies against the same target such as MUC18 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Bone Marrow, Brain, Embryonic Tissue, Lung, Muscle, Prostate, Skin, Vascular tissues are correlated with this protein. MUC18 also interacts with the following gene(s): ATF3, CYP1B1, EDN1, ESR1, FGF2, LGALS1, PTK2, TGFB1. Adenocarcinoma, Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Inflammation, Lung Diseases, Lung Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Prostatic Neoplasms are some of the diseases may be linked to Rabbit anti-Human Cell surface glycoprotein MUC18 polyclonal Antibody, FITC.