anti-MCTS1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-MCTS1 antibody; MCTS1;
The MCTS1 mcts1 (Catalog #MBS2521446) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MCTS1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s MCTS1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).WB: 1:200-1:1000
IHC: 1:50-1:200. Researchers should empirically determine the suitability of the MCTS1 mcts1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MCTS1 mcts1 product has the following accession number(s) (GI #63101207) (NCBI Accession #AAH95461.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MCTS1 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Jurkat and K562 cell, PC3 and A549 cell using MCTS1 Polyclonal Antibody at dilution of 1:200)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human colon cancer using MCTS1 Polyclonal Antibody at dilution of 1:30)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human esophagus cancer using MCTS1 Polyclonal Antibody at dilution of 1:30)
MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5\'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.
Immunogen: Recombinant protein of human MCTS1
Calculated Molecular Weight: 21kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MCTS1 are readily searchable from our website. Different antibodies against the same target such as MCTS1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.