anti-MEI1 antibody product blog
Tags: Antibody; Polyclonal Antibody; MEI1; anti-MEI1 antibody;
The MEI1 mei1 (Catalog #MBS2518348) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MEI1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s MEI1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).IHC: 1:25-1:100. Researchers should empirically determine the suitability of the MEI1 mei1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MEI1 mei1 product has the following accession number(s) (GI #90403581) (NCBI Accession #NP_689726.3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MEI1 Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MEI1 Polyclonal Antibody at dilution 1:20)
The predominant cause of spermatogenic arrest of meiosis is the failure of homologous chromosomes to accurately synapse. MEI1 (Meiosis inhibitor protein 1), also designated Meiosis defective protein 1, is a 1274 amino acid protein that is likely required for the formation of genetically programmed double-strand breaks, the first step in the initiation of meiosis. With predominant expression in testis, it is likely that defects of the gene encoding MEI1 results in male infertility. Interestingly, studies show that genetic variation in the MEI gene possibly predisposes European Americans but not Israeli men to infertility by meiotic arrest. Human MEI1 shares 79% sequence similarity with its mouse homolog. There are seven isoforms of MEI1 that are produced as a result of alternative splicing events.
Immunogen: Recombinant protein of human MEI1. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MEI1 are readily searchable from our website. Different antibodies against the same target such as MEI1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Kidney Diseases, Oligospermia are some of the diseases may be linked to MEI1 Polyclonal Antibody. Kidney, Ovary, Testis tissues are correlated with this protein. MEI1 also interacts with the following gene(s): RAD51, SPO11.