|The MELK melk (Catalog #MBS628247) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MELK, CT (Maternal Embryonic Leucine Zipper Kinase, hMELK, HPK38, KIAA0175, pEg3 Kinase, Protein Kinase PK38, RP11-8N6.1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s MELK can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500. Researchers should empirically determine the suitability of the MELK melk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MELK melk product has the following accession number(s) (GI #7661974) (NCBI Accession #NP_055606.1) (Uniprot Accession #Q14680). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
MELK Contains 1 protein kinase domain that Belongs to the Ser/Thr protein kinase family. It phosphorylates ZNF622 and may contribute to its redirection to the nucleus. MELK may also be involved in the inhibition of spliceosome assembly during mitosis.
Immunogen: Synthetic peptide selected from the C-terminal region of human MELK (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MELK are readily searchable from our website. Different antibodies against the same target such as MELK may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Breast Neoplasms, Cardiovascular Diseases, Cell Transformation, Neoplastic, Fibrosis, Hypertension, Inflammation, Kidney Diseases, Necrosis, Neoplasms, Nervous System Diseases are some of the diseases may be linked to MELK, CT (Maternal Embryonic Leucine Zipper Kinase, hMELK, HPK38, KIAA0175, pEg3 Kinase, Protein Kinase PK38, RP11-8N6.1). MELK also interacts with the following gene(s): ASPM, NCAPG, PBK, ZNF622. Blood, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Spleen, Vascular tissues are correlated with this protein.