|The MEP1B mep1b (Catalog #MBS7045259) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MEP1B Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s MEP1B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the MEP1B mep1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MEP1B mep1b product has the following accession number(s) (GI #815890920) (NCBI Accession #NP_001295100.1) (Uniprot Accession #Q16820). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MEP1B Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot
All lanes: MEP1B antibody IgG at 2.36ug/ml+ Mouse kidney tissue
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 80 kDa
Observed band size: 80 kDa
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human small intestine using MBS7045259 at dilution 1:100)
Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1\' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components.
Immunogen: Recombinant human Meprin A subunit beta protein (480-652AA). Conjugate: Non-conjugated
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23491. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MEP1B are readily searchable from our website. Different antibodies against the same target such as MEP1B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Acute Kidney Injury, Fibrosis, Kidney Diseases, Liver Diseases, Liver Neoplasms, Necrosis are some of the diseases may be linked to MEP1B Antibody. The following patways have been known to be associated with this gene. Intestine, Lymph, Muscle tissues are correlated with this protein.