|The MGMT mgmt (Catalog #MBS1491619) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Methylated-DNA-protein-cysteine methyltransferase polyclonal Antibody, Biotin conjugated reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Methylated-DNA-protein-cysteine methyltransferase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the MGMT mgmt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MGMT mgmt product has the following accession number(s) (GI #530394832) (NCBI Accession #XP_005252739.1) (Uniprot Accession #P16455). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Storage Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate: Biotin. Immunogen: Recombinant human Methylated-DNA--protein-cysteine methyltransferase
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-8825 / sc-8824 / sc-8826 / sc-28241. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MGMT are readily searchable from our website. Different antibodies against the same target such as MGMT may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Intestine, Liver, Lung, Lymph, Skin, Stomach, Vascular tissues are correlated with this protein. MGMT also interacts with the following gene(s): HIF1A, HRAS, KRAS, MLH1, MYB, NRAS, TP53, UBC. Adenocarcinoma, Brain Neoplasms, Carcinoma, Carcinoma, Squamous Cell, Glioblastoma, Glioma, Lung Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Recurrence are some of the diseases may be linked to Rabbit anti-human Methylated-DNA-protein-cysteine methyltransferase polyclonal Antibody, Biotin conjugated.