anti-MMP-14 antibody product blog
Tags: Antibody; Polyclonal Antibody; MMP-14; anti-MMP-14 antibody;
The MMP-14 mmp14 (Catalog #MBS9400770) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MMP-14 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s MMP-14 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the MMP-14 mmp14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MMP-14 mmp14 product has the following accession number(s) (GI #4826834) (NCBI Accession #NP_004986.1) (Uniprot Accession #P50281). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MMP-14 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from NIH/3T3 cells, using MMP-14 antibody.)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MMP-14 antibody.)
Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase An on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.Bimal K. Ray, Circ. Res., Nov 2004; 95: 1082 - 1090. Sharon Elliot, Invest. Ophthalmol. Vis. Sci., Apr 2006; 47: 1696 - 1702. Hongqing Q. Ye, Invest. Ophthalmol. Vis. Sci., Sep 2000; 41: 2894. Leanne J. Bakke, Biol Reprod, Jun 2002; 66: 1627.
Immunogen Type: Peptide
Immunogen Description: Synthesized peptide derived from human MMP-14. Target Name: MMP-14. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MMP-14 are readily searchable from our website. Different antibodies against the same target such as MMP-14 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. MMP-14 also interacts with the following gene(s): FURIN, MMP2, SP1, TIMP1, TIMP2. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Disease Models, Animal, Fibrosis, Inflammation, Liver Neoplasms, Lung Diseases, Lung Neoplasms, Necrosis, Neoplasm Invasiveness are some of the diseases may be linked to MMP-14 Antibody. Blood, Bone, Brain, Connective Tissue, Embryonic Tissue, Heart, Lung, Muscle, Skin, Vascular tissues are correlated with this protein.