|The MORF4 n/a (Catalog #MBS150101) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MORF4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s MORF4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).
MORF4 antibody can be used for the detection of MORF4 by Western blot at 1 and 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the MORF4 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MORF4 n/a product has the following accession number(s) (GI #14917016) (NCBI Accession #AAD29871) (Uniprot Accession #Q9Y690). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MORF4 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of MORF4 in K562 cell lysate with MORF4 antibody at (A) 1 and (B) 2 μg/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of MORF4 in human brain tissue with MORF4 antibody at 5 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of MORF4 in HepG2 cells with MORF4 antibody at 20 μg/mL.)
MORF4 Antibody: Cellular senescence is the terminal non-dividing state that normal cells enter following completion of their proliferative potential. Fusions of immortal human cell lines with each other have led to their assignment to one of four complementation groups. Mortality factor 4 (MORF4) was identified as the lead member of a family of transcription factor-like proteins that reverses this immortal phenotype. Like other members in this family, MORF4 is localized to the nucleus and possesses transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that might allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.
Immunogen: MORF4 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human MORF4.
Buffer: MORF4 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MORF4 are readily searchable from our website. Different antibodies against the same target such as MORF4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.