|The MTMR4 n/a (Catalog #MBS626838) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Myotubularin Related Protein 4, CT (MTMR4, FYVE Domain-containing Dual Specificity Protein Phosphatase 2, FYVE-DSP2, KIAA0647, Zinc Finger FYVE Domain-containing Protein 11, ZFYVE11) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Myotubularin Related Protein 4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:10-1:50. Researchers should empirically determine the suitability of the MTMR4 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MTMR4 n/a product has the following accession number(s) (GI #217272865) (NCBI Accession #NP_004678.3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
MTMR, a member of the myotubularin family, encodes an intracellular protein of 1,195 amino acids, and shares approximately 47% sequence identity with MTMR3, spiking to over 70% identity in the catalytic domain and the double zinc finger (FYVE) motif. PCR analysis detects expression of MTMR4 in all human tissues examined except lung, small intestine, stomach, salivary gland, adrenal gland, and uterus. Subcellular localization of MTMR4 in transfected HeLa cells showed a perinuclear distribution, similar to that seen with MTMR3. MTMR4 dephosphorylates para-nitrophenylphosphate and phosphatidylinositol 3-phosphate.
Immunogen: Synthetic peptide selected from the C-terminal region of human MTMR4 (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MTMR4 are readily searchable from our website. Different antibodies against the same target such as MTMR4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Bone, Brain, Connective Tissue, Ear, Embryonic Tissue, Heart, Kidney, Muscle, Umbilical Cord, Vascular tissues are correlated with this protein.