|The LRP mvp (Catalog #MBS6007593) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LRP, CT (Major Vault Protein, Lung Resistance-related Protein, MVP) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s LRP can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the LRP mvp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The LRP mvp product has the following accession number(s) (GI #19577290) (NCBI Accession #CAA56256.2) (Uniprot Accession #Q14764). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
MVP, the major vault protein, is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance.
Immunogen: Synthetic peptide selected from the C-terminal region of human MVP (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing LRP are readily searchable from our website. Different antibodies against the same target such as LRP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. LRP also interacts with the following gene(s): ABCB1, ABCC1, ABCC3, PTEN, PTPN11, STAT1, YPEL4. Bladder, Blood, Bone, Brain, Connective Tissue, Heart, Liver, Lung, Muscle, Vascular tissues are correlated with this protein. Brain Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Hypertension, Hypertrophy, Myocardial Infarction, Neoplasm Metastasis, Neoplasms, Neurobehavioral Manifestations are some of the diseases may be linked to LRP, CT (Major Vault Protein, Lung Resistance-related Protein, MVP).