anti-NAE1 antibody product blog
Tags: Antibody; Polyclonal Antibody; NAE1; anti-NAE1 antibody;
The NAE1 nae1 (Catalog #MBS128767) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NAE1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s NAE1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB: 1:500-1:2000. Researchers should empirically determine the suitability of the NAE1 nae1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NAE1 nae1 product has the following accession number(s) (GI #50400302) (NCBI Accession #Q13564.1) (Uniprot Accession #Q13564). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NAE1 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using NAE1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 10s.)
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer\'s disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, an ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
Species: Human
Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human NAE1
Calculated Molecular Weight: 60kDa. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NAE1 are readily searchable from our website. Different antibodies against the same target such as NAE1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Breast Neoplasms, Liver Neoplasms are some of the diseases may be linked to NAE1 Polyclonal Antibody. NAE1 also interacts with the following gene(s): APP, NEDD8, UBA3. Brain, Heart, Kidney, Liver, Lung, Muscle, Skin tissues are correlated with this protein.