|The NDUFS4 ndufs4 (Catalog #MBS2520443) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NDUFS4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s NDUFS4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).
IHC: 1:50-1:200. Researchers should empirically determine the suitability of the NDUFS4 ndufs4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NDUFS4 ndufs4 product has the following accession number(s) (GI #4505369) (NCBI Accession #NP_002486.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NDUFS4 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Mouse kidney and heart tissue using NDUFS4 Polyclonal Antibody at dilution of 1:200)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human colon cancer using NDUFS4 Polyclonal Antibody at dilution of 1:20)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human brain using NDUFS4 Polyclonal Antibody at dilution of 1:20)
This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane.
Immunogen: Recombinant protein of human NDUFS4
Calculated Molecular Weight: 20kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NDUFS4 are readily searchable from our website. Different antibodies against the same target such as NDUFS4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Death, Disease Models, Animal, Heart Diseases, Inflammation, Leigh Disease, Liver Diseases, Mitochondrial complex I deficiency, Nerve Degeneration, Nervous System Diseases, Parkinson Disease are some of the diseases may be linked to NDUFS4 Polyclonal Antibody.