anti-NEDD4L antibody product blog
Tags: Antibody; Polyclonal Antibody; NEDD4L; anti-NEDD4L antibody;
The NEDD4L nedd4l (Catalog #MBS6009377) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NEDD4L, ID (NEDD4L, KIAA0439, NEDL3, E3 ubiquitin-protein ligase NEDD4-like, NEDD4.2, Nedd4-2) reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s NEDD4L can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500. Researchers should empirically determine the suitability of the NEDD4L nedd4l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NEDD4L nedd4l product has the following accession number(s) (GI #21619660) (NCBI Accession #AAH32597.1) (Uniprot Accession #Q96PU5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NEDD4L, ID (NEDD4L, KIAA0439, NEDL3, E3 ubiquitin-protein ligase NEDD4-like, NEDD4.2, Nedd4-2) with the following immunoassay(s):
Western Blot (WB) (NEDD4L Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the NEDD4L antibody detected the NEDD4L protein (arrow).)
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK.
Immunogen: NEDD4L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-604 amino acids from the Central region of human NEDD4L. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NEDD4L are readily searchable from our website. Different antibodies against the same target such as NEDD4L may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Carcinoma, Hepatocellular, Disease Models, Animal, Heart Diseases, Hyperplasia, Hypertension, Kidney Diseases, Learning Disorders, Neoplasms, Pancreatic Neoplasms, Prostatic Diseases are some of the diseases may be linked to NEDD4L, ID (NEDD4L, KIAA0439, NEDL3, E3 ubiquitin-protein ligase NEDD4-like, NEDD4.2, Nedd4-2).