anti-NEIL1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-NEIL1 antibody; NEIL1;
The NEIL1 neil1 (Catalog #MBS649896) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NEIL1, ID (NEIL1, Endonuclease 8-like 1, DNA glycosylase/AP lyase Neil1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Endonuclease VIII-like 1, FPG1, Nei homolog 1, Nei-like protein 1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s NEIL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:50-100. Researchers should empirically determine the suitability of the NEIL1 neil1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NEIL1 neil1 product has the following accession number(s) (GI #14790078) (NCBI Accession #AAH10876.1) (Uniprot Accession #Q96FI4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NEIL1, ID (NEIL1, Endonuclease 8-like 1, DNA glycosylase/AP lyase Neil1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Endonuclease VIII-like 1, FPG1, Nei homolog 1, Nei-like protein 1) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of NEIL1 Antibody (Center) in A2058 cell line lysates (35ug/lane). NEIL1 (arrow) was detected using the purified Pab.)
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).
Immunogen: NEIL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137~167 amino acids from the Central region of human NEIL1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NEIL1 are readily searchable from our website. Different antibodies against the same target such as NEIL1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. NEIL1 also interacts with the following gene(s): FEN1, HUS1, LIG3, NEIL3, NTHL1, OGG1, PCNA, POLB, XRCC1. Blood, Brain, Heart, Kidney, Liver, Lung, Lymph Node, Muscle, Spleen, Thymus tissues are correlated with this protein.