Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Polyclonal Antibody Blog  rightarrow anti-NES antibody  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
 • anti-FIS1 antibody blog
 • anti-TP53RK antibody blog
 • anti-SEZ6L antibody blog
 • anti-KEAP1 antibody blog
 • anti-DDX20 antibody blog
 • anti-FLJ11730 antibody blog
 • anti-DCAMKL3 antibody blog
 • anti-CHEK2 antibody blog
 • anti-DZIP3 antibody blog
 • anti-PRKD2 antibody blog
 • anti-CES1 antibody blog
 • anti-POU2F1 antibody blog
 • anti-PAICS antibody blog
 • anti-SPRY1 antibody blog
 • anti-cIAP2 antibody blog
 • anti-EZR antibody blog
 • anti-GNaZ antibody blog
 • anti-HTR7 antibody blog
 • anti-PARP6 antibody blog
 • anti-PDHB antibody blog
Blog Categories separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
Our Best Sellers moreseparator
 • Polycystin-1 (PKD1) Recombinant Protein
 • Dengue Virus (Pan) Envelope Antibody
 • SHP-1 Antibody
 • NT-Pro Brain Natriuretic Recombinant Protein
 • transcobalamin II; macrocytic anemia (TCN2) Antibody
 • PGCA Antibody
 • Osteonectin ELISA Kit
 • 5-aminolevulinate synthase, nonspecific, mitochondrial (ALAS... Recombinant Protein
 • Granulocyte Chemotactic Protein 2 (GCP2) ELISA Kit
 • VPS45 Antibody
 • Proenkephalin (PENK) Peptide
 • Vitamin D Binding Protein (GC) ELISA Kit
 • placental lactogen (CSH1) Recombinant Protein
 downarrow more ...

anti-NES antibody product blog

Posted on 2015-12-19 08:49:41 by mybiosource_staff
Share it on ...     
Tags: Antibody; NES; Polyclonal Antibody; anti-NES antibody;
The NES prf1 (Catalog #MBS859018) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NES Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s NES can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the NES prf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The NES prf1 product has the following accession number(s) (GI #133908621) (NCBI Accession #NP_001076585.1) (Uniprot Accession #P14222). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NES Antibody with the following immunoassay(s):
Testing Data (Western blot analysis of extracts of various celllines,using PRF1 antibody.)
Testing Data NES.

Background: Granzymes are a family of serine proteases expressed by cytotoxic T lymphocytes and natural killer (NK) cells and are key components of immune responses to pathogens and transformed cells (1). Granzymes are synthesized as zymogens and are processed into mature enzymes by cleavage of a leader sequence. They are released by exocytosis in lysosome-like granules containing perforin, a membrane pore-forming protein. Granzyme B has the strongest apoptotic activity of all the granzymes as a result of its caspase-like ability to cleave substrates at aspartic acid residues thereby activating procaspases directly and cleaving downstream caspase substrates (2,3). Perforin is a pore-forming protein that facilitates the entry of cytotoxic serine proteases, such as granzymes, into target cells (4). Perforin is primarily expressed in cytotoxic T lymphocytes and NK cells.

Immunogen: Recombinant protein of human PRF1
Species: Rabbit. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NES are readily searchable from our website. Different antibodies against the same target such as NES may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. NES also interacts with the following gene(s): CD247, CD3E, CD80, CD86, EOMES, GZMB, IL2, IL2RA, IL2RB. Carcinoma, Cardiovascular Diseases, Heart Diseases, Inflammation, Kidney Diseases, Liver Diseases, Lung Neoplasms, Lymphoma, Non-Hodgkin, Necrosis, Neoplasms, Experimental are some of the diseases may be linked to NES Antibody.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions