anti-Neurofilament L, 68kD antibody product blog
Tags: Antibody; Polyclonal Antibody; Neurofilament L, 68kD; anti-Neurofilament L, 68kD antibody;
The Neurofilament L, 68kD n/a (Catalog #MBS6000777) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Neurofilament L, 68kD (NF-L, NFL, 68kD Neurofilament Protein, CMT1F, CMT2E, NEFL, Neurofilament Light Polypeptide 68kD, NF68, Neurofilament Triplet L Protein) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Neurofilament L, 68kD can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP).Suitable for use in Western Blot and Immunoprecipitation. Researchers should empirically determine the suitability of the Neurofilament L, 68kD n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below:
MSSFSYEPYY STSYKRRYVE TPRVHISSVR SGYSTARSAY SSYSAPVSSS LSVRRSYSSS SGSLMPSLEN LDLSQVAAIS NDLKSIRTQE KAQLQDLNDR FASFIERVHE LEQQNKVLEA ELLVLRQKHS EPSRFRALYE QEIRDLRLAA EDATNEKQAL QGEREGLEET LRNLQARYEE EVLSREDAEG RLMEARKGAD EAALARAELE KRIDSLMDEI SFLKKVHEEE IAELQAQIQY AQISVEMDVT KPDLSAALKD IRAQYEKLAA KNMQNAEEWF KSRFTVLTES AAKNTDAVRA AKDEVSESRR LLKAKTLEIE ACRGMNEALE KQLQELEDKQ NADISAMQDT INKLENELRT TKSEMARYLK EYQDLLNVKM ALDIEIAAYR KLLEGEETRL SFTSVGSITS GYSQSSQVFG RSAYGGLQTS SYLMSTRSFP SYYTSHVQEE QIEVEETIEA AKAEEAKDEP PSEGEAEEEE KDKEEAEEEE AAEEEEAAKE ESEEAKEEEE GGEGEEGEET KEAEEEEKKV EGAGEEQAAK KKD.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Neurofilament L, 68kD (NF-L, NFL, 68kD Neurofilament Protein, CMT1F, CMT2E, NEFL, Neurofilament Light Polypeptide 68kD, NF68, Neurofilament Triplet L Protein) with the following immunoassay(s):
Western Blot (WB) (NEFL rabbit polyclonal antibody. Western Blot analysis of NEFL expression in Hela NE.)
Western Blot (WB) (Western Blot analysis of NEFL expression in transfected 293T cell line by NEFL polyclonal antibody. Lane 1: NEFL transfected lysate (61.5kD). Lane 2: Non-transfected lysate.)
Immunoprecipitation (IP) (Immunoprecipitation of NEFL transfected lysate using NEFL rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with NEFL purified mouse polyclonal antibody)
Neurofilaments are the intermediate filaments found in neuronal cells. They are composed of a combination of subunit proteins which typically includes the neurofilment triplet proteins, NF-L (68kD), NF-M (160kD), and NF-H (200kD). Neurofilaments may also include peripherin, alpha-internexin (NF66), nestin, and vimentin. Antibodies to the various neurofilament subunits are useful biomarkers; the filaments are abundant and biochemically stable. The expression of neurofilament proteins varies during neuronal development and differentiation and between between neuronal cell subtypes, and altered in pathological states. Accumulation of neurofilaments is observed the progression of numerous neurological diseases.
Immunogen: Full length human NEFL, aa1-543 (NP_006149.2). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Neurofilament L, 68kD are readily searchable from our website. Different antibodies against the same target such as Neurofilament L, 68kD may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.