|The NFATc2 nfatc2 (Catalog #MBS536130) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NFATc2 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s NFATc2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the NFATc2 nfatc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NFATc2 nfatc2 product has the following accession number(s) (GI #27886541) (NCBI Accession #NP_775114) (Uniprot Accession #Q13469). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Affinity purified Rabbit polyclonal NFATc2 antibody.
Biological Significance: The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that coordinate the immune response. NFATc is the cytosolic component of NFAT and encoded by a separate gene. Expression of NFATc activates the interleukin (IL-2) promoter in non-T lymphocytes and is required for IL-2 gene expression. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen: NFATc2 antibody was raised in rabbit using residues 269-281 [ASPQRSRSPSPQP] of the human NFATc2 protein as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NFATc2 are readily searchable from our website. Different antibodies against the same target such as NFATc2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Brain Diseases, Disease Models, Animal, Heart Diseases, Hypertrophy, Immune System Diseases, Inflammation, Lung Diseases, Necrosis, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to NFATc2 antibody. Blood, Brain, Embryonic Tissue, Heart, Lung, Lymph, Lymph Node, Skin, Spleen, Thymus tissues are correlated with this protein. NFATc2 also interacts with the following gene(s): EGR1, FOS, FOXP3, IL2, IL4, IRF4, JUN, MAPK8, MEF2D.