|The NFkB p105 nfkb1 (Catalog #MBS5300281) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NFkB p105 antibody (Ser932) reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s NFkB p105 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
IHC: 1:50-1:100. Researchers should empirically determine the suitability of the NFkB p105 nfkb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NFkB p105 nfkb1 product has the following accession number(s) (GI #259155302) (NCBI Accession #NP_001158884.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NFkB p105 antibody (Ser932) with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using NFkB p105 antibody (Ser932))
Western Blot (WB) (Western blot analysis of extracts from HeLa cells, untreated or treated with TNFalpha (20ng/ml 5min) and Calyculin A (50nM 15min), using NFkappaB p105/p50 antibody and NFkB p105 antibody (Ser932) (Lanes 3 and 4))
Rabbit Polyclonal NFkB p105 antibody (Ser932).
Biological Significance: NFkB p105 is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. Immunogen: NFkB p105 antibody was raised in Rabbit using a synthesized phosphopeptide derived from human NFkB p105 around the phosphorylation site of serine 932 (E-T-SP-F-R) as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NFkB p105 are readily searchable from our website. Different antibodies against the same target such as NFkB p105 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. NFkB p105 also interacts with the following gene(s): BCL3, BIRC3, CHUK, EP300, HDAC1, IKBKB, MAP3K8, NFKBIA, RELA. The following patways have been known to be associated with this gene. Adenocarcinoma, Brain Diseases, Cardiovascular Diseases, Cell Transformation, Neoplastic, Disease Models, Animal, Heart Diseases, Inflammation, Liver Diseases, Necrosis, Nervous System Diseases are some of the diseases may be linked to NFkB p105 antibody (Ser932).