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anti-NKX6-1 antibody product blog

Posted on 2015-08-30 02:43:30 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; NKX6-1; anti-NKX6-1 antibody;
The NKX6-1 nkx6-1 (Catalog #MBS642547) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NKX6-1, CT (NKX6-1, NKX6A, Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s NKX6-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500. Researchers should empirically determine the suitability of the NKX6-1 nkx6-1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The NKX6-1 nkx6-1 product has the following accession number(s) (GI #1894911) (NCBI Accession #AAD11962.1) (Uniprot Accession #P78426). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM].

NKX6-1 nkx6-1

Immunogen: NKX6-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-314 amino acids from the C-terminal region of human NKX6-1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NKX6-1 are readily searchable from our website. Different antibodies against the same target such as NKX6-1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. NKX6-1 also interacts with the following gene(s): FGF10, FOXA2, FOXO1, GCG, ISL1, NEUROD1, NEUROG3, NKX2-2, ONECUT1, PTF1A. The following patways have been known to be associated with this gene. Pancreas tissues are correlated with this protein. Adenoma, Brain Diseases, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 2, Disease Models, Animal, Hyperglycemia, Hyperplasia, Hypoglycemia, Spinal Cord Diseases, Weight Loss are some of the diseases may be linked to NKX6-1, CT (NKX6-1, NKX6A, Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A).
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