anti-NLRP6 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-NLRP6 antibody; NLRP6;
The NLRP6 nlrp6 (Catalog #MBS9207781) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NLRP6 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s NLRP6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:1000. Researchers should empirically determine the suitability of the NLRP6 nlrp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NLRP6 nlrp6 product has the following accession number(s) (GI #452085173) (NCBI Accession #NP_001263629.1) (Uniprot Accession #P59044). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NLRP6 Antibody (N-term) with the following immunoassay(s):
Western Blot (WB) (NLRP6Antibody (N-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the NLRP6 antibody detected the NLRP6 protein (arrow).)
NALPs are cytoplasmic proteins that form a subfamily
within the larger CATERPILLER protein family. Most short NALPs,
such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain
(PYD), followed by a NACHT domain, a NACHT-associated domain (NAD),
and a C-terminal leucine-rich repeat (LRR) region. The long NALP,
NALP1 (MIM 606636), also has a C-terminal extension containing a
function to find domain (FIIND) and a caspase recruitment domain
(CARD). NALPs are implicated in the activation of proinflammatory
caspases (e.g., CASP1; MIM 147678) via their involvement in
multiprotein complexes called inflammasomes (Tschopp et al., 2003
[PubMed 12563287]).
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NLRP6 are readily searchable from our website. Different antibodies against the same target such as NLRP6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Disease Models, Animal, Fatty Liver, Fatty Liver, Alcoholic, Hypertension, Inflammation, Liver Cirrhosis, Liver Diseases, Necrosis, Vascular Diseases are some of the diseases may be linked to NLRP6 Antibody (N-term). NLRP6 also interacts with the following gene(s): PYCARD. Blood, Intestine, Kidney, Testis tissues are correlated with this protein.