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anti-NOD1 antibody product blog

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Posted on 2015-08-01 00:07:20 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; anti-NOD1 antibody; NOD1;
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The NOD1 nod1 (Catalog #MBS151197) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NOD1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s NOD1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).
NOD1 antibody can be used for detection of NOD1 by Western blot at 1 mug/mL. Researchers should empirically determine the suitability of the NOD1 nod1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The NOD1 nod1 product has the following accession number(s) (GI #20137579) (NCBI Accession #Q9Y239.1) (Uniprot Accession #Q9Y239). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NOD1 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of NOD1 in EL4 cell lysate with NOD1 antibody at 1 μg/mL.)
Western Blot (WB) NOD1.

NOD1 Antibody: NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-κB. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.

Conjugate: Unconjugated
Immunogen: NOD1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy end of human NOD1.
Buffer: NOD1 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NOD1 are readily searchable from our website. Different antibodies against the same target such as NOD1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. NOD1 also interacts with the following gene(s): CARD6, CASP1, CASP8, IL1B, NOS2, RIPK2, SUGT1, TRAF3. The following patways have been known to be associated with this gene.
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