anti-NP antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-NP antibody; Influenza A Virus Nucleoprotein;
The NP np (Catalog #MBS1488853) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Influenza A virus Nucleoprotein polyclonal Antibody, HRP conjugated reacts with Influenza A virus and may cross-react with other species as described in the data sheet. MyBioSource\'s Influenza A virus Nucleoprotein can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the NP np for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The NP np product has the following accession number(s) (GI #8486130) (NCBI Accession #NP_040982.1) (Uniprot Accession #P03466). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein\'s nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein\'s nuclear localization signals, targeting the RNP to the nucleus.
Storage Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate: HRP. Immunogen: Recombinant Influenza A virus Nucleoprotein protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NP are readily searchable from our website. Different antibodies against the same target such as NP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.