anti-NPHS2 antibody product blog
Tags: Antibody; Polyclonal Antibody; NPHS2; anti-NPHS2 antibody;
The NPHS2 nphs2 (Catalog #MBS415609) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NPHS2 Antibody reacts with Human, Mouse, Rat. Not yet tested in other species. and may cross-react with other species as described in the data sheet. MyBioSource\'s NPHS2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).Peptide ELISA titer: 1:5,000-1:20,000
Western blot analysis: 1:200-500
Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the NPHS2 nphs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NPHS2 nphs2 product has the following accession number(s) (GI #20809646) (NCBI Accession #AAH29141.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-NPHS2 Antibody with the following immunoassay(s):
Testing Data
This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].
Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide. Immunogen: Rabbit polyclonal NPHS2 antibody was raised against a peptide from near the C terminal residues of human NPHS2 protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NPHS2 are readily searchable from our website. Different antibodies against the same target such as NPHS2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Kidney tissues are correlated with this protein. Albuminuria, Glomerulonephritis, Glomerulosclerosis, Focal Segmental, Hypertension, Kidney Diseases, Kidney Failure, Chronic, Nephrosis, Nephrotic Syndrome, Proteinuria, Renal Insufficiency are some of the diseases may be linked to Anti-NPHS2 Antibody. NPHS2 also interacts with the following gene(s): CD2AP, FYN, GRB2, KIRREL, KIRREL3, TRPC6.