anti-NR1H4 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-NR1H4 antibody; NR1H4;
The NR1H4 nr1h4 (Catalog #MBS9205292) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NR1H4 Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. MyBioSource\'s NR1H4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:1000. Researchers should empirically determine the suitability of the NR1H4 nr1h4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NR1H4 nr1h4 product has the following accession number(s) (GI #332801015) (NCBI Accession #NP_001193906.1) (Uniprot Accession #Q96RI1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NR1H4 Antibody (N-term) with the following immunoassay(s):
Western Blot (WB) (NR1H4 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the NR1H4 antibody detected the NR1H4 protein (arrow).)
NR1H4 is a Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NR1H4 are readily searchable from our website. Different antibodies against the same target such as NR1H4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Carcinoma, Hepatocellular, Cholestasis, Disease Models, Animal, Fatty Liver, Inflammation, Insulin Resistance, Intestinal Neoplasms, Liver Diseases, Liver Neoplasms, Non-alcoholic Fatty Liver Disease are some of the diseases may be linked to NR1H4 Antibody (N-term). Adrenal Gland, Bladder, Blood, Brain, Connective Tissue, Heart, Intestine, Kidney, Liver, Ovary tissues are correlated with this protein. NR1H4 also interacts with the following gene(s): ABCB11, CYP7A1, NR0B2.