anti-NR6A1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-NR6A1 antibody; NR6A1;
The NR6A1 nr6a1 (Catalog #MBS6005964) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NR6A1 (Nuclear Receptor Subfamily 6 Group A Member 1, Germ Cell Nuclear Factor, GCNF, hGCNF, Retinoid Receptor-related Testis-specific Receptor, RTR, hRTR, GCNF) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s NR6A1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Suitable for use in Western Blot. Researchers should empirically determine the suitability of the NR6A1 nr6a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NR6A1 nr6a1 product has the following accession number(s) (GI #513788273) (NCBI Accession #NP_001265475.1) (Uniprot Accession #Q15406). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MERDEPPPSG GGGGGGSAGF LEPPAALPPP PRNGFCQDEL AELDPGTNDR AEQRTCLICG DRATGLHYGI ISCEGCKGFF KRSICNKRVY RCSRDKNCVM SRKQRNRCQY CRLLKCLQMG MNRKAIREDG MPGGRNKSIG PVQISEEEIE RIMSGQEFEE EANHWSNHGD SDHSSPGNRA SESNQPSPGS TLSSRSVELN GFMAFREQYM GMSVPPHYQY IPHLFSYSGH SPLLPQQARS LDPQSYSLIH QLLSAEDLEP LGTPMLIEDG YAVTQAELFA LLCRLADELL FRQIAWIKKL PFFCELSIKD YTCLLSSTWQ ELILLSSLTV YSKQIFGELA DVTAKYSPSD EELHRFSDEG MEVIERLIYL YHKFHQLKVS NEEYACMKAI NFLNQDIRGL TSASQLEQLN KRYWYICQDF TEYKYTHQPN RFPDLMMCLP EIRYIAGKMV NVPLEQLPLL FKVVLHSCKT SVGKE.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NR6A1 (Nuclear Receptor Subfamily 6 Group A Member 1, Germ Cell Nuclear Factor, GCNF, hGCNF, Retinoid Receptor-related Testis-specific Receptor, RTR, hRTR, GCNF) with the following immunoassay(s):
Western Blot (WB) (NR6A1 rabbit polyclonal antibody. Western Blot analysis of NR6A1 expression in human liver.)
Western Blot (WB) (Western Blot analysis of NR6A1 expression in transfected 293T cell line by NR6A1 polyclonal antibody. Lane 1: NR6A1 transfected lysate (53.9kD). Lane 2: Non-transfected lysate.)
GCNF (Germ Cell Nuclear Factor), also known as NR6A1 (Nuclear Receptor Subfamily 6 Group A member), is an orphan member of the nuclear receptor gene superfamily. It has been shown to be expressed in the nervous system during development and during specific stages in maturing germ cells of the ovary and testis in the adult, and has probable roles in ametogenesis, neurogenesis, and normal embryonic development during gastrulation. Inactivation of GCNF in mouse results in abnormal posterior development, impaired midbrain development, insufficient closure of the neural tube, and eventual embryonic death. GCNF has been shown to be a repressor of OCT-4 and of the protamine genes and plays a critical role in the control of gene expression during embryogenesis and spermatogenesis.