anti-NRP1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-NRP1 antibody; NRP1;
The NRP1 nrp1 (Catalog #MBS9127414) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NRP1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s NRP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).WB: 1:500 - 1:2000
IHC: 1:50 - 1:200. Researchers should empirically determine the suitability of the NRP1 nrp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NRP1 nrp1 product has the following accession number(s) (GI #206729912) (NCBI Accession #O14786.3) (Uniprot Accession #O14786). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NRP1 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of U-251MG cells, using NRP1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 60s.)
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Species: Human
Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human NRP1
Calculated Molecular Weight: 103kDa. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NRP1 are readily searchable from our website. Different antibodies against the same target such as NRP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. NRP1 also interacts with the following gene(s): FLT1, KDR, PGF, PLXNA1, SEMA3A, SEMA3B, SEMA3C, SEMA3E, SEMA3F, VEGFA.