anti-NRXN3 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-NRXN3 antibody; NRXN3; Neurexin 3;
The NRXN3 nrxn3 (Catalog #MBS624956) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The Neurexin 3 (NRXN3, Neurexin 3 Isoform 1 Precursor, KIAA0743, MGC176711, Neurexin III) (Biotin) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Neurexin 3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Suitable for use in Western Blot.
Dilution: Western Blot: 0.1-0.2ug/ml. Researchers should empirically determine the suitability of the NRXN3 nrxn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NRXN3 nrxn3 product has the following accession number(s) (GI #46329869) (Uniprot Accession #Q8IUE3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Neurexins are a family of proteins that function in the vertebrate nervous system as cell adhesion molecules and receptors. They are encoded by several unlinked genes of which two, NRXN1 and NRXN3, are among the largest known human genes. Three of the genes (NRXN1-3) utilize two alternate promoters and include numerous alternatively spliced exons to generate thousands of distinct mRNA transcripts and protein isoforms. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms; a much smaller number of transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins.
Immunogen: Purified, NS0-derived, recombinant human Neurexin 3B. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NRXN3 are readily searchable from our website. Different antibodies against the same target such as NRXN3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Alcohol-Related Disorders, Brain Diseases, Breast Neoplasms, Cognition Disorders, Drug Toxicity, Hypothermia, Learning Disorders, Nervous System Diseases, Prenatal Exposure Delayed Effects, Substance-Related Disorders are some of the diseases may be linked to Neurexin 3 (NRXN3, Neurexin 3 Isoform 1 Precursor, KIAA0743, MGC176711, Neurexin III) (Biotin). NRXN3 also interacts with the following gene(s): NLGN3.