anti-Ntrk2 antibody product blog
Tags: Antibody; NTRK2; Polyclonal Antibody; anti-NTRK2 antibody; Trk B;
The Ntrk2 ntrk2 (Catalog #MBS502211) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TrkB reacts with Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Trk B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Quality Control: Western blots performed on each lot.
WB: 1:1,000. Researchers should empirically determine the suitability of the Ntrk2 ntrk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Ntrk2 ntrk2 product has the following accession number(s) (GI #253683488) (NCBI Accession #NP_001156640.1) (Uniprot Accession #Q63604). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-TrkB with the following immunoassay(s):
Testing Data
Rabbit polyclonal antibody.
Antigen: Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat TrkB.
Immunogen Information: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
Immunogen Species: Rat. Species Reactivity Note: The antibody has been directly tested for reactivity in rat.
Biological Significance: Tropomyosin-receptor-kinase (TRK) receptors are members of the receptor tyrosine kinase family and include TrkA, TrkB and TrkC. Each of these receptor types has different binding affinities to the neurotrophins nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT-3). TrkB has the highest affinity to binding BDNF which plays critical roles in the function and survival of neurons in the CNS (Soppet et al., 1991; Klein et al., 1991). Additionally, alterations in expression of TrkB have been associated with Alzheimer\'s disease (Ferrer et al., 1999; Chen et al., 2008). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Ntrk2 are readily searchable from our website. Different antibodies against the same target such as Ntrk2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Cardiovascular Diseases, Disease Models, Animal, Inflammation, Memory Disorders, Mental Disorders, Neoplasms, Nerve Degeneration, Nervous System Diseases, Neuroblastoma, Pain are some of the diseases may be linked to Anti-TrkB. Adrenal Gland, Brain, Connective Tissue, Dorsal Root Ganglion, Eye, Inner Ear, Nerve, Ovary, Pancreas, Pituitary Gland tissues are correlated with this protein.