anti-NTSR1 antibody product blog
Tags: Antibody; Polyclonal Antibody; Ntsr1; anti-NTSR1 antibody; NTSR1 / NTR;
The NTSR1 ntsr1 (Catalog #MBS247047) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human NTSR1 / NTR reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s NTSR1 / NTR can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA).ELISA (1:1000), IHC-P (5 ug/ml), WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the NTSR1 ntsr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NTSR1 ntsr1 product has the following accession number(s) (GI #110611243) (NCBI Accession #NP_002522.2) (Uniprot Accession #P30989). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal (IgG) to Human NTSR1 / NTR with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-NTSR1 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Western Blot (WB) (Western blot of extracts from MCF7 cells, using NTSR1 antibody. The lane on the right is treated with the synthesized peptide.)
NTR1, a Neurotensin Receptor, activates a phosphatidylinositol-calcium second messenger system in the central and peripheral nervous systems. It mediates the functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. Neurotensin Receptor 1 expression is enhanced in pancreatic cancer and in chronic pancreatitis (Wang et al, 2000).
Target Species: Human
Immunogen Description: Synthetic peptide from human NTR1 (aa181-230). Immunogen: NTSR1 / NTR antibody was raised against synthetic peptide from human NTR1 (aa181-230).
Antigen Modification: aa181-230. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NTSR1 are readily searchable from our website. Different antibodies against the same target such as NTSR1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. NTSR1 also interacts with the following gene(s): NMU, NTS. The following patways have been known to be associated with this gene. Brain Diseases, Breast Neoplasms, Colonic Neoplasms, Inflammation, Kidney Neoplasms, Lung Neoplasms, Nervous System Diseases, Pancreatic Neoplasms, Respiratory Tract Diseases, Schizophrenia are some of the diseases may be linked to Rabbit Polyclonal (IgG) to Human NTSR1 / NTR.