anti-NUMA1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-NUMA1 antibody; NUMA1;
The NUMA1 numa1 (Catalog #MBS9413704) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NUMA1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s NUMA1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the NUMA1 numa1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NUMA1 numa1 product has the following accession number(s) (GI #557440899) (NCBI Accession #NP_001273490.1) (Uniprot Accession #Q14980). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NUMA1 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from A549 cells, using NUMA1 antibody.)
Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human testis tissue using NUMA1 antibody.)
Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions.Yang C.H., J. Cell Biol. 116:1303-1317(1992).Compton D.A., J. Cell Biol. 116:1395-1408(1992).Maekawa T., J. Cell Sci. 105:589-600(1993).
Immunogen Type: Peptide
Immunogen Description: Synthesized peptide derived from internal of human NUMA1. Target Name: NUMA1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NUMA1 are readily searchable from our website. Different antibodies against the same target such as NUMA1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adenocarcinoma, Brain Diseases, Breast Neoplasms, Disease Models, Animal, Liver Neoplasms, Lung Diseases, Nervous System Diseases, Ovarian Diseases, Ovarian Neoplasms, Prostatic Diseases are some of the diseases may be linked to NUMA1 Antibody. The following patways have been known to be associated with this gene. NUMA1 also interacts with the following gene(s): AURKA, CCNB1, CDK1, EPB41L1, NEDD1, SMC3. Blood, Bone, Bone Marrow, Brain, Connective Tissue, Kidney, Lung, Muscle, Nerve, Skin tissues are correlated with this protein.