|The NUP88 nup88 (Catalog #MBS647975) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NUP88, CT (NUP88, Nuclear pore complex protein Nup88, 88kD nucleoporin, Nucleoporin Nup88) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s NUP88 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500. Researchers should empirically determine the suitability of the NUP88 nup88 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NUP88 nup88 product has the following accession number(s) (GI #24497453) (NCBI Accession #NP_002523.2) (Uniprot Accession #Q99567). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias.
Immunogen: NUP88 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 700-730 amino acids from the C-terminal region of human NUP88. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NUP88 are readily searchable from our website. Different antibodies against the same target such as NUP88 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. NUP88 also interacts with the following gene(s): NUP107, NUP153, NUP214, NUP62, NUP93, RAE1, XPO1. Breast Neoplasms, Carcinoma, Carcinoma, Hepatocellular, Cell Transformation, Neoplastic, Liver Diseases, Neoplasm Invasiveness, Neoplasm Metastasis, Ovarian Neoplasms, Uterine Cervical Neoplasms, Weight Loss are some of the diseases may be linked to NUP88, CT (NUP88, Nuclear pore complex protein Nup88, 88kD nucleoporin, Nucleoporin Nup88). Blood, Embryonic Tissue, Kidney, Lung, Lymph Node, Prostate, Skin, Stomach, Uterus, Vascular tissues are correlated with this protein.