|The p27Kip1 n/a (Catalog #MBS649350) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The p27Kip1, phosphorylated (T197) (Cdkn1b, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1) reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s p27Kip1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Gel Shift Assay (GS/EMSA).
Suitable for use in Dot Blot, ELISA
Dilution: ELISA: 1:1,000
Dot blot 1:500. Researchers should empirically determine the suitability of the p27Kip1 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The p27Kip1 n/a product has the following accession number(s) (GI #4587316) (NCBI Accession #BAA76715.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq].
Immunogen: Mouse p27Kip1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T197 of mouse p27Kip1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing p27Kip1 are readily searchable from our website. Different antibodies against the same target such as p27Kip1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.