anti-p56-LCK (LSK) antibody product blog
Tags: Antibody; Polyclonal Antibody; p56-LCK (LSK); anti-p56-LCK (LSK) antibody;
The p56-LCK (LSK) n/a (Catalog #MBS462156) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti p56lck Polyclonal antibody reacts with Human, Rat, Mouse, Bovine, Canine and may cross-react with other species as described in the data sheet. MyBioSource\'s p56-LCK (LSK) can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot, Immunohistochemistry.Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml. Researchers should empirically determine the suitability of the p56-LCK (LSK) n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit anti p56lck Polyclonal antibody with the following immunoassay(s):
Testing Data
Lymphocyte specific protein tyrosine kinase (LCK) belongs to Src family protein-tyrosine kinase. It is essential for T-cell development and function. The activity p56lckis regulated by phosphorylation and dephosphorylation of two critical tyrosine residues Tyr394 and Tyr505. Tyr394 and Tyr505 are autophosphorylated after p56lck activation, whereas phosphorylation of Tyr505 is believed to be due to p50csk which negatively modulates P56lck activity. Autophosphorylation at Tyr505 of P56lck may represent an accessory mechanism for the down-regulation of the tyrosine kinase activity of P56lck.
Antigen Preparation: A synthetic peptide derived from Carboxyl-terminus of p56lck protein from human, rat, bovine, dog origin. Positive Control: Jurkat cells
Cellular Location: Cytoplasmic. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing p56-LCK (LSK) are readily searchable from our website. Different antibodies against the same target such as p56-LCK (LSK) may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.