|The p57KIP2 cdkn1c (Catalog #MBS9406812) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The p57KIP2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s p57KIP2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).
Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the p57KIP2 cdkn1c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The p57KIP2 cdkn1c product has the following accession number(s) (GI #4557441) (NCBI Accession #NP_000067.1) (Uniprot Accession #P49918). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the p57KIP2 Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human brain tissue, using p57KIP2 antibody.)
Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.Matsuoka S., Genes Dev. 9:650-662(1995).Reid L.H., Cancer Res. 56:1214-1218(1996).Tokino T., Hum. Genet. 97:625-631(1996).
Immunogen Type: Peptide
Immunogen Description: Synthesized peptide derived from internal of human p57KIP2. Target Name: p57KIP2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing p57KIP2 are readily searchable from our website. Different antibodies against the same target such as p57KIP2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Brain, Embryonic Tissue, Eye, Heart, Kidney, Liver, Muscle, Placenta, Skin tissues are correlated with this protein. Adenocarcinoma, Beckwith-Wiedemann Syndrome, Breast Neoplasms, Cell Transformation, Neoplastic, Disease Models, Animal, Fetal Growth Retardation, Hyperplasia, Kidney Diseases, Liver Diseases, Liver Neoplasms are some of the diseases may be linked to p57KIP2 Antibody. p57KIP2 also interacts with the following gene(s): BMP10, CCND1, CCNE2, CDK2, CDK4, CDK6, MYOD1, PCNA, SKP2.