anti-PAPPA antibody product blog
Tags: Antibody; Polyclonal Antibody; PAPPA; anti-PAPPA antibody;
The PAPPA pappa (Catalog #MBS2517731) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAPPA Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s PAPPA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).IHC: 1:50-1:200. Researchers should empirically determine the suitability of the PAPPA pappa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PAPPA pappa product has the following accession number(s) (GI #223590248) (NCBI Accession #Q13219.3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PAPPA Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PAPPA Polyclonal Antibody at dilution of 1:50)
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.
Immunogen: Synthetic peptide of human PAPPA. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PAPPA are readily searchable from our website. Different antibodies against the same target such as PAPPA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone, Bone Marrow, Brain, Eye, Heart, Liver, Lung, Muscle, Thyroid, Vascular tissues are correlated with this protein. PAPPA also interacts with the following gene(s): IGF1, IGF2, IGFBP4, IGFBP5, PRG2. Brain Diseases, Heart Diseases, Hypertension, Inflammation, Lung Diseases, Necrosis, Nervous System Diseases, Pain, Uterine Cervical Neoplasms, Uterine Neoplasms are some of the diseases may be linked to PAPPA Polyclonal Antibody. The following patways have been known to be associated with this gene.