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anti-PARP3 antibody product blog

Posted on 2015-08-30 08:50:00 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; PARP3; anti-PARP3 antibody;
The PARP3 parp3 (Catalog #MBS247200) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human PARP3 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PARP3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), ELISA (EIA).
ELISA (1:1000), IHC-P (10 ug/ml). Researchers should empirically determine the suitability of the PARP3 parp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The PARP3 parp3 product has the following accession number(s) (GI #158634482) (NCBI Accession #NP_005476.3) (Uniprot Accession #Q9Y6F1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal (IgG) to Human PARP3 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-PARP3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.)
Immunohistochemistry (IHC) PARP3.

The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.

Target Species: Human
Immunogen Description: Synthetic peptide from human PARP3 (aa10-59). Immunogen: PARP3 antibody was raised against synthetic peptide from human PARP3 (aa10-59).
Antigen Modification: aa10-59. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PARP3 are readily searchable from our website. Different antibodies against the same target such as PARP3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Disease Models, Animal, Necrosis, Nervous System Diseases, Skin Neoplasms are some of the diseases may be linked to Rabbit Polyclonal (IgG) to Human PARP3. Blood, Brain, Intestine, Kidney, Liver, Lung, Nerve, Ovary, Skin, Testis tissues are correlated with this protein. PARP3 also interacts with the following gene(s): PARP1. The following patways have been known to be associated with this gene.
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