anti-PCSK6 antibody product blog
Tags: Antibody; Polyclonal Antibody; PCSK6; anti-PCSK6 antibody;
The PCSK6 pcsk6 (Catalog #MBS643538) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The PCSK6, ID (PACE4, Proprotein Convertase Subtilisin/Kexin Type 6, Paired Basic Amino Acid Cleaving Enzyme 4, Subtilisin-like Proprotein Convertase 4, SPC4, Subtilisin/Kexin-like Protease PACE4) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PCSK6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC).Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:32,000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml. Researchers should empirically determine the suitability of the PCSK6 pcsk6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PCSK6 pcsk6 product has the following accession number(s) (GI #20336188) (NCBI Accession #NP_612196.1) (Uniprot Accession #P29122). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PCSK6, ID (PACE4, Proprotein Convertase Subtilisin/Kexin Type 6, Paired Basic Amino Acid Cleaving Enzyme 4, Subtilisin-like Proprotein Convertase 4, SPC4, Subtilisin/Kexin-like Protease PACE4) with the following immunoassay(s):
Immunohistochemistry (IHC) (Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC) (Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE))
PACE4 is a Serine S8 type protease that cleaves precursor proteins at paired basic amino acid processing sites. Several PACE4 substrates have been identified, including transforming growth factor beta-related proteins, proalbumin and von Willebrand factor. At least eight alternatively spliced transcript variants encoding different isoforms have been reported. In mouse, PACE4 has been shown to increase tumor cell invasiveness, and thus enhance tumor progression.
Immunogen: Synthetic peptide C-YHTFSAHQSRSR from an internal region of human PCSK6. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PCSK6 are readily searchable from our website. Different antibodies against the same target such as PCSK6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Intestine, Kidney, Liver, Lung, Ovary, Placenta, Prostate, Skin, Spleen tissues are correlated with this protein. The following patways have been known to be associated with this gene.