anti-PDE10A2 antibody product blog
Tags: Antibody; Polyclonal Antibody; PDE10A2; anti-PDE10A2 antibody;
The PDE10A2 pde10a (Catalog #MBS540678) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDE10A2 Antibody reacts with Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s PDE10A2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB).Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:200
Western Blot: 1:500. Researchers should empirically determine the suitability of the PDE10A2 pde10a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PDE10A2 pde10a product has the following accession number(s) (GI #4894717) (NCBI Accession #AAD32596.1) (Uniprot Accession #Q9Y233). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PDE10A2 Antibody with the following immunoassay(s):
Western Blot (WB)
Affinity Purified Phosphodiesterase 10A2 Antibody
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.
Immunogen: Synthetic peptide taken within amino acid region 1-50 on human PDE10A2 protein.
Expression: Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum. Molecular Function: Hydrolase, metal-ion binding, cGMP binding
Structure: Homodimer
Subcellular Location: Cytoplasm. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PDE10A2 are readily searchable from our website. Different antibodies against the same target such as PDE10A2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Eye, Intestine, Kidney, Lung, Muscle, Pancreas, Pituitary Gland, Testis, Thyroid tissues are correlated with this protein. Brain Diseases, Cognition Disorders, Disease Models, Animal, Hyperkinesis, Learning Disorders, Memory Disorders, Movement Disorders, Nervous System Diseases, Neurobehavioral Manifestations, Weight Loss are some of the diseases may be linked to PDE10A2 Antibody. PDE10A2 also interacts with the following gene(s): ADCY5.