|The PDK4 pdk4 (Catalog #MBS641545) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDK4, CT (PDK4, PDHK4, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s PDK4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100. Researchers should empirically determine the suitability of the PDK4 pdk4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PDK4 pdk4 product has the following accession number(s) (GI #4505693) (NCBI Accession #NP_002603.1) (Uniprot Accession #Q16654). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Immunogen: PDK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382~411 amino acids from the C-terminal region of human PDK4. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PDK4 are readily searchable from our website. Different antibodies against the same target such as PDK4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adipose Tissue, Brain, Connective Tissue, Heart, Kidney, Liver, Muscle, Nerve, Pancreas, Thyroid tissues are correlated with this protein. PDK4 also interacts with the following gene(s): FOXO1, FOXO3, INS, PDHA1, UCP3. The following patways have been known to be associated with this gene. Cardiovascular Diseases, Fatty Liver, Heart Diseases, Hyperglycemia, Hypertrophy, Inflammation, Insulin Resistance, Liver Diseases, Necrosis, Weight Loss are some of the diseases may be linked to PDK4, CT (PDK4, PDHK4, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4).