anti-PINK1 antibody product blog
Tags: Antibody; Polyclonal Antibody; PINK1; anti-PINK1 antibody; PINK1 (PARK6);
The PINK1 pink1 (Catalog #MBS9200682) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PINK1 (PARK6) Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s PINK1 (PARK6) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:1000. Researchers should empirically determine the suitability of the PINK1 pink1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PINK1 pink1 product has the following accession number(s) (GI #14165272) (NCBI Accession #NP_115785.1) (Uniprot Accession #Q9BXM7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PINK1 (PARK6) Antibody (Center) with the following immunoassay(s):
Western Blot (WB) (The anti-PINK1 C-term Pab is used in Western blot to detect PINK1 in mouse heart tissue lysate.)
Western Blot (WB) (Park6 (PINK1) Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the Park6 (PINK1) antibody detected the Park6 (PINK1) protein (arrow).)
Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson\'s disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson\'s disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PINK1 are readily searchable from our website. Different antibodies against the same target such as PINK1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. PINK1 also interacts with the following gene(s): BECN1, HTRA2, MFN2, PARK2, PARK7, RHOT1, TOMM20, TRAP1. Blood, Brain, Eye, Ganglia, Heart, Kidney, Liver, Lung, Muscle, Nerve tissues are correlated with this protein.