anti-PLXDC1 antibody product blog
Tags: Antibody; Polyclonal Antibody; TEM7; anti-PLXDC1 antibody; PLXDC1;
The PLXDC1 plxdc1 (Catalog #MBS150549) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TEM7 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s TEM7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).TEM7 antibody can be used for detection of TEM7 by Western blot at 0.5 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the PLXDC1 plxdc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PLXDC1 plxdc1 product has the following accession number(s) (GI #14017379) (NCBI Accession #AAG00869) (Uniprot Accession #Q8IUK5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TEM7 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of TEM7 in human liver tissue lysate with TEM7 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of TEM7 in mouse liver tissue with TEM7 antibody at 2.5 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of TEM7 in mouse liver tissue with TEM7 antibody at 20 μg/mL.)
TEM7 Antibody: Tumor endothelial marker 7 (TEM7) was identified through serial analysis of gene expression on endothelial cells isolated from human normal and malignant colorectal tissues. Further experiments verified TEM7 was highly expressed in the endothelium of numerous other cancer types including breast, lung and brain tumors. At least four isoforms of TEM7 are known to exist; these include intracellular, secreted, and membrane-bound forms. A homologous protein, TEM7R (also known as PLXDC2), acts as a binding partner to TEM7 and is also abundantly expressed in the endothelium of malignant colorectal cancer but is absent or rare in normal colon mucosa. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma.
Conjugate: Unconjugated
Immunogen: TEM7 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human TEM7.
Buffer: TEM7 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PLXDC1 are readily searchable from our website. Different antibodies against the same target such as PLXDC1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.