|The PMAIP1 pmaip1 (Catalog #MBS9402064) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PMAIP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PMAIP1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).
Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the PMAIP1 pmaip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PMAIP1 pmaip1 product has the following accession number(s) (GI #10863923) (NCBI Accession #NP_066950.1) (Uniprot Accession #Q13794). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PMAIP1 Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/50.)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using at dilution 1/50.)
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 By similarity. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Immunogen Type: Recombinant Protein
Immunogen Description: Full length fusion protein. Target Name: PMAIP1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PMAIP1 are readily searchable from our website. Different antibodies against the same target such as PMAIP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Brain, Embryonic Tissue, Kidney, Liver, Lung, Lymph Node, Skin tissues are correlated with this protein. Adenocarcinoma, Breast Neoplasms, Cardiovascular Diseases, Leukemia, Lymphocytic, Chronic, B-Cell, Lung Diseases, Lung Neoplasms, Melanoma, Multiple Myeloma, Necrosis, Nervous System Diseases are some of the diseases may be linked to PMAIP1 Antibody. PMAIP1 also interacts with the following gene(s): BAK1, BBC3, BCL2L1, BCL2L11, BID, MCL1, MYC, TP53.