|The PMP22 pmp22 (Catalog #MBS2003454) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Peripheral Myelin Protein 22 (PMP22) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Peripheral Myelin Protein 22 (PMP22) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB).
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the PMP22 pmp22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PMP22 pmp22 product has the following accession number(s) (GI #4505907) (NCBI Accession #NP_000295.1) (Uniprot Accession #Q01453). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-MLL LLLSIIV LHVAVLVLLF VSTIVSQWIV GNGHATDLWQ NCSTSSSGNV HHCFSSSPNE WLQSVQATMI LSIIFSILSL FLFFCQLFTL TKGGRFYITG IFQILAGLCV MSAAAIYTVR HPEWHLNSDY SYGFAYILAW VAFPLALLSG VIYVILRKRE.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Polyclonal Antibody to Peripheral Myelin Protein 22 (PMP22) with the following immunoassay(s):
Western Blot (WB) ((Figure. Western Blot; Sample: Recombinant protein.))
Immunohistochemistry (IHC) ((Figure.DAB staining on IHC-P. Samples: Human Tissue))
Immunogen: Recombinant PMP22 (Met1~Glu160) expressed in E.coli. Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2067961. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PMP22 are readily searchable from our website. Different antibodies against the same target such as PMP22 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. PMP22 also interacts with the following gene(s): CDRT1, CLDN11, GJB1, KIF1B, MED25, MPZ, POU3F1, SH3TC2. Brain Diseases, Charcot-Marie-Tooth Disease, Demyelinating Diseases, Disease Models, Animal, Hereditary Sensory and Motor Neuropathy, Muscle Weakness, Nerve Degeneration, Nervous System Diseases, Peripheral Nervous System Diseases, Tomaculous neuropathy are some of the diseases may be linked to Polyclonal Antibody to Peripheral Myelin Protein 22 (PMP22).