anti-POLR1D antibody product blog
Tags: Antibody; POLR1D; anti-POLR1D antibody; Polyclonal Antibody;
The POLR1D polr1d (Catalog #MBS6002829) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The POLR1D (DNA-directed RNA Polymerases I and III Subunit RPAC2, AC19, DNA-directed RNA Polymerase I Subunit D, RNA Polymerase I 16kD Subunit, RPC16, hRPA19, FLJ20616, MGC9850) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s POLR1D can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Suitable for use in Western Blot. Researchers should empirically determine the suitability of the POLR1D polr1d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The POLR1D polr1d product has the following accession number(s) (GI #31455208) (NCBI Accession #AAH06972.1) (Uniprot Accession #Q9Y2S0). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MEEDQELERK ISGLKTSMAE GERKTALEMV QAAGTDRHCV TFVLHEEDHT LGNSLRYMIM KNPEVEFCGY TTTHPSESKI NLRIQTRGTL PAVEPFQRGL NELMNVCQHV LDKFEASIKD YKDQKASRNE STF.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the POLR1D (DNA-directed RNA Polymerases I and III Subunit RPAC2, AC19, DNA-directed RNA Polymerase I Subunit D, RNA Polymerase I 16kD Subunit, RPC16, hRPA19, FLJ20616, MGC9850) with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of POLR1D expression in transfected 293T cell line by POLR1D polyclonal antibody. Lane 1: POLR1D transfected lysate (15.2kD). Lane 2: Non-transfected lysate.)
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3\'-5\' proofreading exonuclease activity. Forms a Schiff base with 5\'-deoxyribose phosphate at abasic sites, but does not have lyase activity.
Immunogen: Full length human POLR1D, aa1-133 (NP_057056.1). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing POLR1D are readily searchable from our website. Different antibodies against the same target such as POLR1D may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.