anti-PRICKLE2 antibody product blog
Tags: Antibody; Polyclonal Antibody; PRICKLE2; anti-PRICKLE2 antibody;
The PRICKLE2 prickle2 (Catalog #MBS9128776) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRICKLE2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PRICKLE2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF).WB 1:500 - 1:2000
IF 1:50 - 1:100. Researchers should empirically determine the suitability of the PRICKLE2 prickle2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PRICKLE2 prickle2 product has the following accession number(s) (GI #38524620) (NCBI Accession #NP_942559.1) (Uniprot Accession #Q7Z3G6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PRICKLE2 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using PRICKLE2 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.)
Immunofluorescence (IF) (Immunofluorescence analysis of A549 cells using PRICKLE2 antibody.)
This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5.
Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human PRICKLE2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PRICKLE2 are readily searchable from our website. Different antibodies against the same target such as PRICKLE2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Abnormalities, Multiple, Carcinoma, Squamous Cell, Congenital Abnormalities, Fibrosis, Learning Disorders, Lung Neoplasms, Movement Disorders, Neural Tube Defects are some of the diseases may be linked to PRICKLE2 Polyclonal Antibody. Brain, Embryonic Tissue, Eye, Kidney, Lung, Mammary Gland, Prostate, Skin, Testis, Uterus tissues are correlated with this protein. PRICKLE2 also interacts with the following gene(s): ANKRD6, CELSR1, CELSR2, CELSR3, DVL1, DVL2, DVL3, FZD3, VANGL1, VANGL2. The following patways have been known to be associated with this gene.