anti-PTF1A antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-PTF1A antibody; PTF1A;
The PTF1A ptf1a (Catalog #MBS6000448) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Ptf1a, NT (PTF1A, BHLHA29, PTF1P48, Pancreas transcription factor 1 subunit alpha, Class A basic helix-loop-helix protein 29, Pancreas-specific transcription factor 1a, bHLH transcription factor p48, p48 DNA-binding subunit of transcription factor PTF1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Ptf1a can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:50-100
Immunohistochemistry: 1:10-50. Researchers should empirically determine the suitability of the PTF1A ptf1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PTF1A ptf1a product has the following accession number(s) (GI #30039710) (NCBI Accession #NP_835455.1) (Uniprot Accession #Q7RTS3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Ptf1a, NT (PTF1A, BHLHA29, PTF1P48, Pancreas transcription factor 1 subunit alpha, Class A basic helix-loop-helix protein 29, Pancreas-specific transcription factor 1a, bHLH transcription factor p48, p48 DNA-binding subunit of transcription factor PTF1) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of Ptf1a (arrow) using rabbit polyclonal Ptf1a Antibody (N-term).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Ptf1a gene (Lane 2) (Origene Technologies).)
Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human brain tissue reacted with Ptf1a Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Ptf1a is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. This protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in the Ptf1a gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.
Immunogen: Ptf1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Ptf1a.