|The PTP1B ptpn1 (Catalog #MBS859567) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTP1B (Ab-50) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s PTP1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).
WB: 1:500~1:1000, IHC: 1:50~1:100, ELISA: 1:20000. Researchers should empirically determine the suitability of the PTP1B ptpn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PTP1B ptpn1 product has the following accession number(s) (GI #519666804) (NCBI Accession #NP_001265547.1) (Uniprot Accession #P18031). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PTP1B (Ab-50) Antibody with the following immunoassay(s):
Testing Data #2 (Immunohistochemistry analysis of paraffin-embedded human brain tissue using PTP1B (Ab-50) antibody.
Western blot analysis of extracts from COS7 cells, treated with UV (30mins), using PTP1B (Ab-50) antibody.)
Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human PTP1B around the phosphorylation site of serine 50 (D-V-SP-P-F). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PTP1B are readily searchable from our website. Different antibodies against the same target such as PTP1B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Brain, Connective Tissue, Heart, Kidney, Liver, Lung, Muscle, Pancreas, Vascular tissues are correlated with this protein. Cardiovascular Diseases, Diabetes Mellitus, Type 2, Disease Models, Animal, Glucose Intolerance, Hyperglycemia, Inflammation, Insulin Resistance, Liver Diseases, Necrosis, Weight Gain are some of the diseases may be linked to PTP1B (Ab-50) Antibody. PTP1B also interacts with the following gene(s): AKT1, BCAR1, EGFR, GRB2, INSR, IRS1, JAK2, SRC, TRPV6.