anti-RANGAP1 antibody product blog
Tags: Antibody; Polyclonal Antibody; RANGAP1; anti-RANGAP1 antibody;
The RANGAP1 rangap1 (Catalog #MBS242446) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Xenopus RANGAP1 reacts with Xenopus, HumanPredicted Reactivity: Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Rabbit, Chicken, Zebrafish (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s RANGAP1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB).
IF, IHC-P (1:100), WB (1:500 - 1:1000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the RANGAP1 rangap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The RANGAP1 rangap1 product has the following accession number(s) (GI #4506411) (NCBI Accession #NP_002874.1) (Uniprot Accession #P46060). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Xenopus RANGAP1 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-RANGAP1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Immunohistochemistry (IHC) (Anti-RANGAP1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p.
Target Species: Xenopus
Immunogen Description: A mixture of two peptides from Xenopus RanGAP, n-CHWSDMFTGRLRPEI-c & n-CPSPEKLVRMGPRRSA-. Immunogen: RANGAP1 antibody was raised against a mixture of two peptides from Xenopus RanGAP, n-CHWSDMFTGRLRPEI-c & n-CPSPEKLVRMGPRRSA-. Percent identity by BLAST analysis: Xenopus (100%); Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Opossum, Turkey, Chicken, Platypus, Lizard, Zebrafish (93%); Seabass, Salmon, Stickleback, Pufferfish (87%); Nematode (80%). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RANGAP1 are readily searchable from our website. Different antibodies against the same target such as RANGAP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.