anti-RETN antibody product blog
Tags: Antibody; Resistin; Polyclonal Antibody; RETN; anti-RETN antibody;
The RETN retn (Catalog #MBS535365) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Resistin antibody reacts with Murine resistin and may cross-react with other species as described in the data sheet. MyBioSource\'s Resistin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). Researchers should empirically determine the suitability of the RETN retn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The RETN retn product has the following accession number(s) (GI #9966777) (NCBI Accession #NP_065148.1) (Uniprot Accession #Q9HD89). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Affinity purified Goat polyclonal Resistin antibody.
Biological Significance: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with an unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin\'s ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Immunogen: Resistin antibody was raised in goat using highly pure recombinant murine resistin as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RETN are readily searchable from our website. Different antibodies against the same target such as RETN may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Atherosclerosis, Cardiovascular Diseases, Diabetes Mellitus, Diabetes Mellitus, Type 2, Heart Diseases, Hypertension, Inflammation, Insulin Resistance, Metabolic Syndrome X, Necrosis are some of the diseases may be linked to Resistin antibody. Blood, Bone Marrow, Eye, Intestine, Placenta tissues are correlated with this protein. RETN also interacts with the following gene(s): ADIPOQ, AKT1, INS, INSR, LEP, PPARA, SERPINE1, TNF, UCP1. The following patways have been known to be associated with this gene.