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anti-RHO antibody product blog

Posted on 2018-02-14 16:18:05 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; Rhodopsin; anti-RHO antibody; RHO;
The RHO rho (Catalog #MBS2539162) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rhodopsin Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Rhodopsin can be used in a range of immunoassay formats including, but not limited to, WB, IHC-p, ELISA.
WB 1:500-2000
IHC 1:100-1:300
ELISA 1:5000. Researchers should empirically determine the suitability of the RHO rho for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The RHO rho product has the following accession number(s) (GI #4506527) (NCBI Accession #NP_000530.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rhodopsin Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of COLO205 cells with Rhodopsin Polyclonal Antibody.)
Western Blot (WB) RHO.

Retinitis pigmentosa is an inherited progressive disease which is a majorcause of blindness in western communities. It can be inherited as anautosomal dominant, autosomal recessive, or X-linked recessive disorder.In the autosomal dominant form,which comprises about 25% of totalcases, approximately 30% of families have mutations in the geneencoding the rod photoreceptor-specific protein rhodopsin. This is thetransmembrane protein which, when photoexcited, initiates the visualtransduction cascade. Defects in this gene are also one of the causes ofcongenital stationary night blindness.RHO (Rhodopsin) is a ProteinCoding gene. Diseases associated with RHO include Night Blindness,Congenital Stationary, Autosomal Dominant 1 and Retinitis Pigmentosa4, Autosomal Dominant Or Recessive. Among its related pathways are thevisual cycle I (vertebrates) and Phototransduction. GO annotations relatedto this gene include G-protein coupled receptor activity and photoreceptoractivity. An important paralog of this gene is OPN1SW.

Immunogen: Synthesized peptide derived from human Rhodopsin around the non-phosphorylation site of S334.
Calculated MW: 39 kDa
Observed MW: 42 kDa
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol pH 7.4. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RHO are readily searchable from our website. Different antibodies against the same target such as RHO may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. RHO also interacts with the following gene(s): GNAT1, GNAT2, GNGT1, GRK1, GRK7, RCVRN, RLBP1, SAG. The following patways have been known to be associated with this gene.
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